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What is Isotonitazene?

Buy Isotonitazene is known to be a benzimidazole derived opioid analgesic drug associated with etonitazene, which is sold mostly as a designer drug in the market. It consists of only about half the potency of etonitazene in animal studies, but it still tends to demonstrate similar strength to that of fentanyl and its analogues. Consequently, isotonitazene is expect to pose a substantial risk of creating hazardous and dangerous respiratory problems. As well as various other typical opioid side effects including nausea, vomiting, sedation, and so on. Buy Isotonitazene Powder

Order Isotonitazene, purchased from an online vendor, was entirely characterized in November 2019 in a paper in which the authors performed a complete analytical structure elucidation. Besides determining the potency of the μ opioid receptor with the help of a biological functional assay in vitro. Get Isotonitazene was not compare directly to morphine in this particular assay, but it was instead found o be around 2.5 times more potent than hydromorphone and even a bit more potent than fentanyl. Buy Isotonitazene Powder

A designer drug can be define as a functional or structural analog of a controll substance which is mainly designe to imitate the pharmacological effects of the original drug. And that too while avoiding classification as . Designer drugs tend to include psychoactive substances designated by the EU as new psychoactive substances or analogs of performance-enhancing drugs. Buy Isotonitazene Powder| isotonitazene controlled drugs uk|isotonitazene controlled drugs uk| isotonitazene iso new york| research chemicals for sale| | research chemical| research chemicals online| chemical raw material suppliers | research chem supply| raw chemicals suppliers| us chemical supply| chem supply| chemical suppliers online usa| chemical materials suppliers| chem supply store| raw chemical suppliers near me

Where to buy Isotonitazene Powder?

Isotonitazene powder for sale  is chemically , N,N-diethyl-2-(2-(4-isopropoxybenzyl)-5-nitro-1H-benzimidazol-1-yl)ethan-1-amine. Chemical syntheses of isotonitazene and other schedule I
synthetic opioid substances containing a benzimidazole core, such as etonitazene and clonitazene, were first reported in the late 1950s.

Data obtained from pre-clinical studies demonstrate that isotonitazene exhibits a pharmacological profile similar to that of etonitazene and other mu-opioid receptor agonists. In an in vivo (in mice) study, isotonitazene was more potent than morphine as
an analgesic in a tail-flick assay. Data from in vitro studies showed that isotonitazene, similar to fentanyl and hydromorphone, activates the mu-opioid receptors. Activation of
the mu-opioid receptors by isotonitazene has been report to involve recruitment of β-arrestin-2, a regulatory protein. Studies have shown that mu-opioid receptor and β-arrestin-2 interaction is implicate in some of the adverse effects of opioid analgesics.